Eylea blocks a substance called VEGF, which is released by areas of retina starved of
oxygen with poor blood flow. VEGF causes vascular leakage and subsequent
swelling of the retina.
Eylea is a is a 115-kD decoy receptor fusion protein comprising the second domain
of human VEGF receptor 1 and the third domain of VEGF receptor 2 fused to the
Fc domain of human immunoglobulin G1.