Michael Colucciello MD       

Medical and Surgical Retina and Macula Consultant                          
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Michael Colucciello MD
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Age-Related Macular Degeneration
Diabetic Retinopathy
Diabetic Retinopathy testing
Non-Proliferative Diabetic Retinoapathy
Proliferative Diabetic Retinopathy
Diabetic Macular Edema
Diabetic Macular Edema treatment: Lucentis
Diabetic Macular Edema treatment: Avastin
Diabetic Macular Edema treatment: Ozurdex
Diabetic Macular Edema treatment: Laser
Proliferative Diabetic Retinopathy treatment:Laser
PDR treatment: Avastin
PDR treatment: Lucentis
PDR treatment: Surgery
Retinal Venous Occlusive Disease
Macular Hole
Macular Pucker
Macular Edema
Central Serous Chorioretinopathy
Retinal Tear
Retinal Detachment
Retinal Arterial disease
Controversies in Care Articles
Michael Colucciello MD Retina Articles
Michael Colucciello MD: Curriculum Vitae
New Custom 1

Proliferative Diabetic Retinopathy occurs when ischemic signals in the retina lead to the formation of new vessels (retinal neovascularization).

These new vessels (highlighted below right in the fluorescein angiogram) have the tendency to bleed in the vitreous cavity of the eye, leading to vision loss, scarring and, with contraction of the scar, tractional retinal detachments that can be associated with permanent vision loss.

Laser photocoagulation, Anti-VEGF medication injections (Avastin, Lucentis) and/or surgery can lead to neovascular regression, quiescence of the retinopathy and stabilization or improvement in vision and quality of life.

Proliferative Diabetic Retinopathy with new vessels at the optic disc ("Neovascularization of the Disc")

The neovascularization has a tendency to bleed, which may obscure vision.