Michael Colucciello MD       

Medical and Surgical Retina and Macula Consultant                          
Macula.us Home
Michael Colucciello MD
Contact Information
Age-Related Macular Degeneration
AMD Testing
Wet AMD treatment: Avastin
Wet AMD treatment: Lucentis
Wet AMD treatment: Eylea
Wet AMD treatment: Visudyne PDT
Diabetic Retinopathy
Retinal Venous Occlusive Disease
Macular Hole
Macular Pucker
Macular Edema
Central Serous Chorioretinopathy
Retinal Tear
Retinal Detachment
Retinal Arterial disease
Controversies in Care Articles
Michael Colucciello MD Retina Articles
Michael Colucciello MD: Curriculum Vitae
New Custom 1

Wet AMD: treatment with Eylea (Aflibercept)

Binding of a substance called VEGF is important in treating retinal diseases associated with vascular leakage and abnormal vascular growth, such as wet AMD.

Eylea (Aflibercept) is a 115-kD decoy receptor fusion protein comprising the second domain of human VEGF receptor 1 and the third domain of VEGF receptor 2 fused to the Fc domain of human immunoglobulin G1.

Subretinal fluid (black area under retina profile) pre-treatment with Eylea (upper left) is absorbed one month following treatment with Eylea (lower left), woth improved vision.