Michael Colucciello MD       

Medical and Surgical Retina and Macula Consultant                          
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Michael Colucciello MD
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Wet AMD treatment: Avastin
Wet AMD treatment: Lucentis
Wet AMD treatment: Eylea
Wet AMD treatment: Visudyne PDT
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Michael Colucciello MD Retina Articles
Michael Colucciello MD: Curriculum Vitae
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Wet AMD: treatment with Eylea (Aflibercept)


Binding of a substance called VEGF is important in treating retinal diseases associated with vascular leakage and abnormal vascular growth, such as wet AMD.

Eylea (Aflibercept) is a 115-kD decoy receptor fusion protein comprising the second domain of human VEGF receptor 1 and the third domain of VEGF receptor 2 fused to the Fc domain of human immunoglobulin G1.


Subretinal fluid (black area under retina profile) pre-treatment with Eylea (upper left) is absorbed one month following treatment with Eylea (lower left).