In wet AMD, Vascular Endothelial Growth Factor (VEGF) triggers the growth of new vessels under the retina, which
may leak blood and fluid into the retina. This causes swelling in and under the retina, which affect retinal function and retinal cellular viability.
Many advances in diagnosis and treatment of wet AMD have occurred
recently and are employed in the practice, including intravitreal Avastin, Lucentis and Eylea treatment, and photodynamic therapy with Visudyne.